The 2016 Annual Forum Topic
Chromosomal Instability & Aneuploidy – 2016
Aneuploidy is a fancy work for an abnormal number of chromosomes in a cell.
Large-scale sequencing efforts have provided unprecedented insight into the genomic changes that occur during the production of tumors. We now understand that chromosomal abnormalities are an almost universal feature of cancer. The challenges we are faced with now is to explain what drives these abnormalities and how can we use this phenomenon in therapeutic intervention. The development of new tools has opened up new ways to tackle these longstanding questions. At the Forum they will be discussing how this affects cancer and fuels tumor evolution. The leaders in the field will discuss the state of their respective fields and way forward to translate this information to the clinic.